HANTAVIRUS
Cases43
Hot zones3
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Year in surveillance

Hantavirus in United States2025

United States hantavirus surveillance — continuing Mono County activity and routine state reporting

Overview

US Sin Nombre virus surveillance through 2025 continued to be dominated by the western and southwestern states — New Mexico, Colorado, Arizona, California, Washington, and Montana — with cumulative case counts of roughly 25–60 per year nationwide, consistent with the multi-decade CDC baseline. Mono County, California remained a watchpoint following the 2024 cluster; state and county health agencies maintained targeted advisories around deer-mouse exposure in the Eastern Sierra. Seoul virus pet-rat surveillance continued at low levels, with periodic case identification through voluntary colony testing.

United States baseline

Syndrome
HPS
Annual cases
25–60/year
CFR
36%
Latest reported
2023

Highest case counts in western and southwestern states (NM, CO, AZ, CA). Sin Nombre virus is the dominant strain.

Source: CDC Hantavirus Surveillance

Relevant strains

References & primary sources

Other years tracked for United States

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